DNN, or DotNetNuke, is an open source ASP.NET content management system that makes it easy for web site owners to keep their websites up to date and dynamic.

Microsoft Dynamics CRM is a customer relationship management solution that makes it easy for business owners to keep in connection with customers and leads throughout the sales cycle and beyond.

Put them together and you have a winning combination.

We have been having some good luck with integrating Microsoft CRM with DNN.  So far we have ported some Web2Lead functionality into a DNN Module.  This will make it very easy for customers who use DNN to load the module and quickly hook it to their CRM system.